منابع مشابه
Discovering lymphocyte subsets
At a scientific meeting in 1968, Jacques Miller was accused of complicating immunology. He and others suggested that there was not one but two kinds of lymphocytes--one from the thymus and one from the bone marrow. In a pair of groundbreaking articles published in the Journal of Experimental Medicine in 1968, Miller and his student Graham Mitchell proved that two subsets of lymphocytes did exis...
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Background: Cytotoxic CD8+ T cells, as essential parts of the adaptive immune system, play pivotal roles in anti-tumor immune responses. It is well documented that cytokine expression profiles and activation status of these cells during anti-tumor immune responses affect the outcome of host-tumor interaction. Objective: To investigate the percentages of CD8+ lymphocytes and their subsets in...
متن کاملLymphocyte subsets and activation.
The biology of lymphocytes is regulated by a large and seemi& growing number of soluble and cell-associated species. A current list includes: interleukins IL l-7, interferons, antigen and perhaps CD4 and cytokines derived from non-lymphoid tissues such as neuropepride, steroid and admnergic hormones. The quality and quantity of regulators present in the B cell milieu during an immunologic insul...
متن کاملHaemophilia and T lymphocyte subsets.
Number of circulating lymphocytes and T cell subsets were assessed in 13 boys with severe haemophilia and 12 age matched controls. There was no significant difference between the two groups. This conflicts with previous findings in adults where lymphopenia and changes in T cell subpopulations have been found frequently.
متن کاملLymphocyte subsets in hypersensitivity pneumonitis.
Hypersensitivity pneumonitis (extrinsic allergic alveolitis) is the pulmonary manifestation of hypersensitivity to various categories of inhaled organic antigens. These include animal proteins from the faeces of pigeons or parakeets, or from duck and turkey feathers and antigens from various plant sources such as mouldy hay, sugar cane, bark and mushrooms. Certain drugs may also produce this re...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2005
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.2011fta